Rising Stars of Regenerative Engineering: Synthetic Artificial Stem Cells – A Platform for Precision Medicine in Regenerative Engineering
Synthetic artificial stem cells (SASC) have been engineered to reproduce the paracrine effect of the stem cell secretome and provide control of its composition for targeted tissue regeneration. During this presentation, various applications of SASC to osteoarthritis (OA) will be described, choosing growth factors important to chondrogenesis and encapsulating respective recombinant proteins in poly (lactic-coglycolic acid) 85:15 (PLGA). SASC demonstrates the feasibility of precision manufacturing a completely synthetic, tailorable secretome for regenerative engineering.
Trainee: Rachel Marchini
Mentor: Lakshmi S. Nair, M.Phil., Ph.D., FBAO, FAIMBE, FNAI, Professor
Department of Orthopedic Surgery, UConn Musculoskeletal Institute
Department of Material Science and Engineering
Department of Biomedical Engineering
Associate Director, The Cato T. Laurencin Institute for Regenerative Engineering
University of Connecticut
Learn more about the webinar series and presenters.
FORMAT: Webinar presentation for 40 minutes by the trainee, followed by a 20-minute dialogue with the mentor, and concluding with 15 additional minutes for Q&A via chat from the audience. The events will be hosted and moderated by Dr. Gualberto Ruaño, Director of Special Projects at The Cato T. Laurencin Institute for Regenerative Engineering, University of Connecticut.
RISING STARS OF REGENERATIVE ENGINEERING: THE DYNAMIC OF STUDENTS AND RESEARCH MENTORS
The Advanced Regenerative Manufacturing Institute (ARMI) is a member-based, nonprofit organization whose mission is to advance the bioeconomy of the United States.
BioFabUSA, a program of ARMI, is a public-private partnership with more than 170 members, including companies, academic institutions and not-for profit organizations.
ARMI BioIndustries is the full-service development and manufacturing operation within the Advanced Regenerative Manufacturing Institute.
NextFab is the first foundry for American biotechnology. The mission of NextFab is to produce technological solutions that help the United States protect against and respond to health-security threats, enhance daily medical care and add to the U.S. bioeconomy.
BioFabUSA, a program of ARMI, is a public-private partnership with more than 170 members, including companies, academic institutions and not-for profit organizations.
